December 11, 2012

Allelic gene expression cattle IGF2 imbalances, mineral wax and the CCL2 genes in liver, kidney and pituitary.

Allele expression imbalance (AEI) is a kind of important genetic factor is the difference of the phenotypic traits, can genetic. The study can be used to find factors that regulate gene expression molecular mechanism, which is helpful to understand the bottom phenotypic change. Although it is generally accepted in many species, and we know that many genes show allele expression imbalance, this kind of phenomenon is not large scale study in cattle. Use pyrophosphoric acid sequencing technology method we analyzed a group of 29 cattle genes in order to find the favorable allele expression. The study investigated in three organization: liver, pituitary and kindey. From the research group of genes and their mineral wax (leptin), IGF2 (insulin-like growth factor 2), the CCL2 (chemokine carbon-carbon bond pattern ligand 2) display allelic expression is not balanced.

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